Translational Findings From Cardiovascular Stem Cell Research

Insights from Ayurveda for translational stem cell research

Ayurveda, the traditional Indian system of medicine has given great emphasis to the promotion of health. Ayurveda therapies are based on restoration of body balance and nourishment of dhatus or tissues. Rasayana concept of Ayurveda explains tissue regeneration and cell renewal. The drugs and therapies explained as rasayana provide research opportunities for biology of regeneration. Specific ras...

Translational development of mesenchymal stem cell therapy for cardiovascular diseases.

Currently, a growing number of small clinical trials are testing the impact of cell-based therapies for heart disease. In order to guide future approaches, it is important in the context of these trials to consider issues pertaining to mechanism of action. To date, the bone marrow has been the most widely studied source of cell-based therapy for heart disease, and this has been followed by skel...

Bringing prosocial values to translational, disease-specific stem cell research

BACKGROUND Disease-specific stem cell therapies, created from induced pluripotent stem cell lines containing the genetic defects responsible for a particular disease, have the potential to revolutionize the treatment of refractory chronic diseases. Given their capacity to differentiate into any human cell type, these cell lines might be reprogrammed to correct a disease-causing genetic defect i...

A critical look at cardiovascular translational research.

Stem Cells in Translational Cancer Research

1Department of Genetics and Evolutionary Biology, Human Genome and Stem Cell Research Center, Biosciences Institute, University of São Paulo, 05508-090 São Paulo, SP, Brazil 2Neurooncology Group, Department of Oncology, Biodonostia Institute, Paseo Dr. Beguiristain s/n, 20014 San Sebastián, Spain 3Department of Surgery and Cancer, Imperial Centre for Translational and Experimental Medicine, Imp...